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Main Street Inn

Top rated by guests
Property building, Garden, Street view
Bed
Floor plan
Autumn
Bedroom
review stars
9.9Outstanding
(17 Ratings)
"Everything about this place is lovely. From the owners to the staff, everyone is very accommodating and they go above and beyond to make your stafy enjoyable. The custom wood work, comfortable beds, n..."
Verified guest
Don't miss out! Price and availability may change
9.9 / 10
Outstanding(17 Ratings)

Bed and Breakfast in South Dakota

3-Star Bed & Breakfast

Reasons to book

Guests love it hereGuests give this property a top rating
Well priced for this locationPriced under area average
Book with confidenceWe partner with the top travel sites so you know you're getting a great deal on the perfect rental

About this bed and breakfast

Comfortable Accommodations

Amenities at Main Street Inn

Free WiFi/internet
Free Parking
Air conditioning
Non-smoking
Heating
WiFi/Internet
Family friendly
Contactless check-in/out
Cleaning products

Map of South Dakota

city location on map

Nearby attractions

Akta Lakota Museum & Cultural Center
140.5 mi
Farm Island
198.6 mi
South Dakota Veterans Park
140.3 mi
South Dakota Hall of Fame
140.3 mi

Available Rooms

Ratings and reviews

9.9 / 10
Outstanding(17 Ratings)
100% verified reviews
10 / 10Outstanding·Aug 2026
Everything about this place is lovely. From the owners to the staff, everyone is very accommodating and they go above and beyond to make your stafy enjoyable. The custom wood work, comfortable beds, nicely updated bathrooms, beverage and snack stations and cozy, clean rooms all make this place a standout. The breakfast was yummy and the little touches go a long way. Plus, you can't beat the location. I plan to stay here every time I come to Vermillion.
10 / 10Outstanding·Aug 2026
We Love staying at the Main Street Inn! It’s a beautiful, homey, Bed & Breakfast with fantastic hosts. The chef style breakfast is Fabulous!
10 / 10Outstanding·Jul 2026
The staff were friendly and helpful. The room was very clean and comfortable. The history of the place was pretty neat.
You had to share a fridge with the other guests, but it wasn't horrible.
10 / 10Outstanding·May 2026
Exceptional property, lovely hosts, fantastic service and the breakfasts!!!
$$$$
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FAQs

Does this property follow enhanced cleaning procedures?

Yes, this bed and breakfast has implemented enhanced cleaning procedures and processes to keep you healthy and safe.

Is parking included with this bed and breakfast?

Parking is not specified as an available amenity at Main Street Inn. For more information, we encourage you to contact the property about where to park.

Is there a pool at this bed and breakfast?

We didn’t find pool listed as an amenity for this bed and breakfast. It may be worth double checking if a pool is important for your stay.

Is Main Street Inn pet friendly?

Unfortunately, this bed and breakfast is not pet-friendly. Try searching again and filter for "Pets Allowed"

What amenities are available at Main Street Inn?

We found 9 amenities for this rental. This includes free wifi/internet, free parking, air conditioning, non-smoking, and heating.