House in Jeffersonville, IN
24 guests · 8 bedrooms · 6 baths
Reasons to book
Guests love it hereGuests give this property a top rating
Great for petsBring all your friends and family, even the furry ones
Top-tier experienceA high end property in this area
About this house rental
🌅 Deaconess Guesthouse | Historic Luxury Riverfront Estate | Dome, Hot Tub, Fire Pit, 8BR, Sleeps 24 | Walk to Jeffersonville + Minutes to Louisville, Derby & Bourbon Trail
Some homes offer a place to stay. Deaconess Guesthouse offers a place to gather, celebrate and create lasting memories.
Welcome to Deaconess Guesthouse, a rare 1800s historic riverfront estate beautifully restored with modern luxury, refined comfort and unforgettable Ohio River views. Designed for elevated group stays, this one-of-a-kind retreat blends timeless architecture, high-end amenities and an unbeatable location just minutes from Downtown Louisville, Churchill Downs, the Kentucky Bourbon Trail and walkable Downtown Jeffersonville.
Wake up to golden riverfront sunrises from expansive wraparound porches. Spend your days exploring bourbon distilleries, Louisville dining, festivals, museums and the iconic Big Four Bridge. As evening falls, unwind in the private hot tub overlooking the river, gather around the fire pit under the stars or relax on the porch as the Ohio River becomes your backdrop.
This is more than a luxury stay — it’s a private riverfront experience designed to bring people together.
★ Luxury Group Living | Historic Charm + Modern Comfort
Thoughtfully restored and beautifully curated, this 8-bedroom, 6-bathroom luxury estate sleeps up to 24 guests, making it one of the premier large-group vacation rentals near Louisville.
Perfect for family reunions, wedding groups, executive retreats, Derby weekends and Bourbon Trail getaways, the estate offers:
• 8 designer bedrooms + 6 bathrooms
• Four private suites, each with its own full kitchen
• Multiple living areas for gathering, relaxing, and privacy
• Spa-inspired bathrooms and elevated finishes
• Expansive wraparound porches with panoramic Ohio River views
• Historic 1800s character blended with modern luxury design
Whether your group wants connection, celebration, or quiet retreat-style comfort, every space is designed to feel both grand and welcoming.
★ Private Riverfront Oasis | Hot Tub, Fire Pit & Outdoor Gathering Spaces
Step outside and enjoy your own exclusive waterfront escape:
• Private hot tub with stunning river views
• Fire pit for cozy evenings and meaningful conversations
• Covered porches and private balconies for sunrise coffee and sunset wine
• Unique stargazing dome experience
• Expansive lawn for games, relaxation, and group gatherings
• Peaceful riverfront setting just minutes from city attractions
From slow mornings on the porch to unforgettable nights by the fire, Deaconess Guesthouse delivers a stay your group will remember.
★ Unbeatable Location | Walkable Jeffersonville + Minutes to Louisville
Enjoy peaceful riverfront luxury with convenient access to the region’s best attractions:
• Walk to Downtown Jeffersonville restaurants, cafés, shops, and festivals
• Stroll across the iconic Big Four Bridge into Louisville
• Minutes to Downtown Louisville, NuLu, Waterfront Park, and 4th Street Live
• Easy access to Churchill Downs and Kentucky Derby events
• Close to Kentucky Bourbon Trail distilleries, museums, nightlife, and major festivals
You get the best of both worlds — a serene riverfront estate with effortless access to Louisville’s top experiences.
★ Perfect For
✔ Kentucky Derby stays and major event weekends
✔ Bourbon Trail group getaways
✔ Family reunions and milestone celebrations
✔ Wedding groups and special occasions
✔ Corporate retreats and executive offsites
✔ Luxury multi-family vacations
★ Why Guests Choose Deaconess Guesthouse
✔ Rare historic riverfront estate near Louisville
✔ Sleeps up to 24 guests comfortably
✔ Four private suites with multiple full kitchens
✔ Private hot tub, fire pit, porches, balconies, and river views
✔ Walkable to Downtown Jeffersonville and Big Four Bridge
✔ Minutes to Churchill Downs, Bourbon Trail, festivals, and Louisville attractions
✔ High-end comfort paired with one-of-a-kind historic character
✨ Your Riverfront Experience Awaits
For guests seeking something truly special — a place with history, elegance, space, and unforgettable views — Deaconess Guesthouse delivers a luxury riverfront experience unlike any other near Louisville.
Highly sought-after dates, including Derby and Bourbon Trail weekends, fill quickly. Reserve your stay and make this historic estate part of your story.
** Please note: A strict cancellation policy applies for Derby and Bourbon & Beyond dates. **
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Waterfront Park - 3.4 miles (9 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- University of Louisville - 6.5 miles (12 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- Valhalla Golf Club - 19 miles (27 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
PREMIUM HIGHLIGHTS
★ Luxury Riverfront Estate, minutes to Louisville & Bourbon Trail: Wake up to panoramic Ohio River views in one of the region’s most coveted locations—just minutes from downtown Louisville, NuLu and world-renowned distilleries.
★ Walkable Waterfront Lifestyle in Historic Jeffersonville: Stroll to scenic parks, boutique shops, cafe's, and top-rated dining. Walk the iconic Big Four Bridge or reach Churchill Downs in 15 minutes—perfect for Derby and major events.
★ Historic Landmark, Beautifully Reimagined: A restored architectural gem featuring soaring ceilings, designer interiors and upscale finishes—blending timeless character with modern luxury.
★ 8BR Estate for Elevated Group Stays: Ideal for family vacations, corporate retreats and celebrations with 8 bedrooms, 6 spa-inspired baths and expansive gathering spaces.
★ Rare 4-Kitchen Experience: Four fully equipped gourmet kitchens—perfect for private chefs, multi-family stays, and effortless entertaining.
★ Resort-Style Indoor-Outdoor Living: Enjoy riverfront lawns, covered porches, balconies, hot tub, fire pit and gazebo dining—perfect for sunset gatherings.
★ Family & Pet-Friendly Luxury: Designed for all ages with comfort, space and thoughtful amenities.
★ Unmatched Access to Louisville’s Best: Bourbon Trail, festivals, nightlife and attractions—then retreat to your private waterfront oasis.
★ 2026 TOP EVENTS
- World Oddities Expo – Jun 13–14, 2026
- Run 4 Roses - Jul 9-14, 2026
- Kentucky State Fair – Aug 20–30, 2026
- Big Four Art Festival – Sep 12–13, 2026
- Louder Than Life – Sep 17–20, 2026
- Bourbon & Beyond – Sep 24–27, 2026
- St. James Court Art Show – Oct 3–4, 2026
- NuLu Fest – Oct 9–11, 2026
- Halloween & Haunted Attractions – Oct 24–31, 2026
- Thanksgiving Week Travel – Nov 25–29, 2026
- Light Up Louisville – Nov 27, 2026
- Christmas at Frazier Museum – Dec 5–20, 2026
- Louisville Ballet: The Nutcracker – Dec 2026
- New Year’s Eve at Fourth Street Live! – Dec 31, 2026
★ 2026 TRADE SHOWS
- World Oddities Expo — Jun 13–14, 2026
- Equip Expo — Oct 20–23, 2026
NOTE:
1. 25+ to book.
2. House Rules Required: E-sign rental agreement and submit a $500 security hold via secure OwnerRez (placed 2 days before arrival, released 7 days after departure if no damage).
3. Cancellation Policy: Please be aware that a strict cancellation policy is in effect for bookings during the Kentucky Derby and Bourbon & Beyond festival dates.
4. No visitors unless pre-approved by the host.
5. Exterior cameras only (parking area & front door). No interior or backyard cameras.
6. Dome use: Not recommended during hot summer months.
7. No early check-in / late check-out on same-day turnovers.
8. When available: $100 (≤2 hrs), $250 (2–4 hrs), full night rate (>4 hrs).
9. Refunds: Non-Airbnb refunds are subject to a 3% payment processing fee.
10. Optional Concierge Services: Enhance your stay with our optional services, including grocery pre-stocking, a private chef experience, or custom-chauffeured Bourbon Trail tours.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANKS!!
Some homes offer a place to stay. Deaconess Guesthouse offers a place to gather, celebrate and create lasting memories.
Welcome to Deaconess Guesthouse, a rare 1800s historic riverfront estate beautifully restored with modern luxury, refined comfort and unforgettable Ohio River views. Designed for elevated group stays, this one-of-a-kind retreat blends timeless architecture, high-end amenities and an unbeatable location just minutes from Downtown Louisville, Churchill Downs, the Kentucky Bourbon Trail and walkable Downtown Jeffersonville.
Wake up to golden riverfront sunrises from expansive wraparound porches. Spend your days exploring bourbon distilleries, Louisville dining, festivals, museums and the iconic Big Four Bridge. As evening falls, unwind in the private hot tub overlooking the river, gather around the fire pit under the stars or relax on the porch as the Ohio River becomes your backdrop.
This is more than a luxury stay — it’s a private riverfront experience designed to bring people together.
★ Luxury Group Living | Historic Charm + Modern Comfort
Thoughtfully restored and beautifully curated, this 8-bedroom, 6-bathroom luxury estate sleeps up to 24 guests, making it one of the premier large-group vacation rentals near Louisville.
Perfect for family reunions, wedding groups, executive retreats, Derby weekends and Bourbon Trail getaways, the estate offers:
• 8 designer bedrooms + 6 bathrooms
• Four private suites, each with its own full kitchen
• Multiple living areas for gathering, relaxing, and privacy
• Spa-inspired bathrooms and elevated finishes
• Expansive wraparound porches with panoramic Ohio River views
• Historic 1800s character blended with modern luxury design
Whether your group wants connection, celebration, or quiet retreat-style comfort, every space is designed to feel both grand and welcoming.
★ Private Riverfront Oasis | Hot Tub, Fire Pit & Outdoor Gathering Spaces
Step outside and enjoy your own exclusive waterfront escape:
• Private hot tub with stunning river views
• Fire pit for cozy evenings and meaningful conversations
• Covered porches and private balconies for sunrise coffee and sunset wine
• Unique stargazing dome experience
• Expansive lawn for games, relaxation, and group gatherings
• Peaceful riverfront setting just minutes from city attractions
From slow mornings on the porch to unforgettable nights by the fire, Deaconess Guesthouse delivers a stay your group will remember.
★ Unbeatable Location | Walkable Jeffersonville + Minutes to Louisville
Enjoy peaceful riverfront luxury with convenient access to the region’s best attractions:
• Walk to Downtown Jeffersonville restaurants, cafés, shops, and festivals
• Stroll across the iconic Big Four Bridge into Louisville
• Minutes to Downtown Louisville, NuLu, Waterfront Park, and 4th Street Live
• Easy access to Churchill Downs and Kentucky Derby events
• Close to Kentucky Bourbon Trail distilleries, museums, nightlife, and major festivals
You get the best of both worlds — a serene riverfront estate with effortless access to Louisville’s top experiences.
★ Perfect For
✔ Kentucky Derby stays and major event weekends
✔ Bourbon Trail group getaways
✔ Family reunions and milestone celebrations
✔ Wedding groups and special occasions
✔ Corporate retreats and executive offsites
✔ Luxury multi-family vacations
★ Why Guests Choose Deaconess Guesthouse
✔ Rare historic riverfront estate near Louisville
✔ Sleeps up to 24 guests comfortably
✔ Four private suites with multiple full kitchens
✔ Private hot tub, fire pit, porches, balconies, and river views
✔ Walkable to Downtown Jeffersonville and Big Four Bridge
✔ Minutes to Churchill Downs, Bourbon Trail, festivals, and Louisville attractions
✔ High-end comfort paired with one-of-a-kind historic character
✨ Your Riverfront Experience Awaits
For guests seeking something truly special — a place with history, elegance, space, and unforgettable views — Deaconess Guesthouse delivers a luxury riverfront experience unlike any other near Louisville.
Highly sought-after dates, including Derby and Bourbon Trail weekends, fill quickly. Reserve your stay and make this historic estate part of your story.
** Please note: A strict cancellation policy applies for Derby and Bourbon & Beyond dates. **
★ CONVENIENT LOCATION
The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins)
- Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins)
- Churchill Downs (DERBY) - 7.7 miles (15 mins)
- KFC Yum Center - 2.3 miles (7 mins)
- Waterfront Park - 3.4 miles (9 mins)
- Louisville Airport - 8.6 miles (10 mins)
- Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins)
- University of Louisville - 6.5 miles (12 mins)
- Kentucky Fairgrounds - 6.5 miles (10 min)
- Kentucky Exposition Center - 6.7 miles (11 mins)
- Kentucky Kingdom - 7.4 miles (13 mins)
- Highland Festival Grounds - 8.5 miles (12 mins)
- Louisville Mega Cavern - 10.2 miles (19 mins)
- UPS Worldport - 11.2 miles (20 mins)
- Ford LAP Plant - 10.9 miles (16 mins)
- Valhalla Golf Club - 19 miles (27 mins)
- Waverly Hills Sanatorium - 17 miles (30 mins)
PREMIUM HIGHLIGHTS
★ Luxury Riverfront Estate, minutes to Louisville & Bourbon Trail: Wake up to panoramic Ohio River views in one of the region’s most coveted locations—just minutes from downtown Louisville, NuLu and world-renowned distilleries.
★ Walkable Waterfront Lifestyle in Historic Jeffersonville: Stroll to scenic parks, boutique shops, cafe's, and top-rated dining. Walk the iconic Big Four Bridge or reach Churchill Downs in 15 minutes—perfect for Derby and major events.
★ Historic Landmark, Beautifully Reimagined: A restored architectural gem featuring soaring ceilings, designer interiors and upscale finishes—blending timeless character with modern luxury.
★ 8BR Estate for Elevated Group Stays: Ideal for family vacations, corporate retreats and celebrations with 8 bedrooms, 6 spa-inspired baths and expansive gathering spaces.
★ Rare 4-Kitchen Experience: Four fully equipped gourmet kitchens—perfect for private chefs, multi-family stays, and effortless entertaining.
★ Resort-Style Indoor-Outdoor Living: Enjoy riverfront lawns, covered porches, balconies, hot tub, fire pit and gazebo dining—perfect for sunset gatherings.
★ Family & Pet-Friendly Luxury: Designed for all ages with comfort, space and thoughtful amenities.
★ Unmatched Access to Louisville’s Best: Bourbon Trail, festivals, nightlife and attractions—then retreat to your private waterfront oasis.
★ 2026 TOP EVENTS
- World Oddities Expo – Jun 13–14, 2026
- Run 4 Roses - Jul 9-14, 2026
- Kentucky State Fair – Aug 20–30, 2026
- Big Four Art Festival – Sep 12–13, 2026
- Louder Than Life – Sep 17–20, 2026
- Bourbon & Beyond – Sep 24–27, 2026
- St. James Court Art Show – Oct 3–4, 2026
- NuLu Fest – Oct 9–11, 2026
- Halloween & Haunted Attractions – Oct 24–31, 2026
- Thanksgiving Week Travel – Nov 25–29, 2026
- Light Up Louisville – Nov 27, 2026
- Christmas at Frazier Museum – Dec 5–20, 2026
- Louisville Ballet: The Nutcracker – Dec 2026
- New Year’s Eve at Fourth Street Live! – Dec 31, 2026
★ 2026 TRADE SHOWS
- World Oddities Expo — Jun 13–14, 2026
- Equip Expo — Oct 20–23, 2026
NOTE:
1. 25+ to book.
2. House Rules Required: E-sign rental agreement and submit a $500 security hold via secure OwnerRez (placed 2 days before arrival, released 7 days after departure if no damage).
3. Cancellation Policy: Please be aware that a strict cancellation policy is in effect for bookings during the Kentucky Derby and Bourbon & Beyond festival dates.
4. No visitors unless pre-approved by the host.
5. Exterior cameras only (parking area & front door). No interior or backyard cameras.
6. Dome use: Not recommended during hot summer months.
7. No early check-in / late check-out on same-day turnovers.
8. When available: $100 (≤2 hrs), $250 (2–4 hrs), full night rate (>4 hrs).
9. Refunds: Non-Airbnb refunds are subject to a 3% payment processing fee.
10. Optional Concierge Services: Enhance your stay with our optional services, including grocery pre-stocking, a private chef experience, or custom-chauffeured Bourbon Trail tours.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANKS!!
Amenities at Waterfront Boutique Estate Views WalknDine Dome Hot Tub Firepit Pets
Non-smoking
Pets allowed
Family friendly
Map of Jeffersonville, IN
Ratings and reviews
10 / 10Outstanding·Jan 2026
We Absolutely Loved Our Stay at Deaconess Guesthouse!We loved everything about this house! The tall ceilings, comfortable sitting areas, and the beautiful color palettes in each unit made it such a special and relaxing place to stay. The promotional boards with bits of history were so fun to read and gave the home extra character.The coffee bar was a huge hit with our group, and the little touches like the ice bucket and fully stocked bathrooms (shampoo, conditioner, and body wash) were so appreciated. It made our stay effortless knowing that everything we needed—paper towels, toilet paper, sponges, towels—was already provided.The place was spotless when we arrived, and it was such a treat to have TVs in every room. We really enjoyed the hot tub, and when we had a small issue, someone came right away—not only to fix it but also to clean it thoroughly. The responsiveness was top-notch. Even when we asked for a vacuum, it was delivered immediately!This property is beautifully maintained and exceptionally well-managed. We would absolutely stay here again and highly recommend it to anyone visiting Jeffersonville or the Louisville area!
10 / 10Outstanding·Dec 2025
The house is big and unique. There are four areas that could be separate spaces - each includes a living area, kitchen, bathroom, and two bedrooms. We were able to gather together when we wanted to and have our own space to sleep. The teens enjoyed the hot tub, and the younger kids liked the games. The location is great. We walked along the river and to the hub of town. Highly recommend.
10 / 10Outstanding·Dec 2025
Another great stay at The Deaconess House! This was a repeat stay for our annual sales and marketing strategic planning and everything about our stay was great! Communication prior to and during the stay was excellent. The property was as described, all 4 units were fully stocked and more than met our needs. We had 8 adults staying plus had visitors one evening for a special dinner and the home provided plenty of room for everyone. We will likely return for a third visit next year and we highly recommend this property!
10 / 10Outstanding·Nov 2025
We had a wonderful experience! Probably the best rental I've ever stayed in. It was very clean, wonderful amenities and the host was very attentive. Checking on us several times. We will highly recommend and hope to stay again!!
$$$$
Top rated by guests
10Outstanding
(22 Ratings)
"We Absolutely Loved Our Stay at Deaconess Guesthouse!We loved everything about this house! The tall ceilings, comfortable sitting areas, and the beautiful color palettes in each unit made it such a sp..."
Michelle C.Don't miss out! Price and availability may change
