House in Jeffersonville, IN
24 guests · 8 bedrooms · 6 baths
Reasons to book
Guests love it hereGuests give this property a top rating
Great for petsBring all your friends and family, even the furry ones
Top-tier experienceA high end property in this area
About this house rental
🌅 Deaconess Guesthouse | Historic Riverfront Luxury Estate Near Louisville | 8BR | Sleeps 24 | Hot Tub | Glass Dome | Fire Pit
Welcome to Deaconess Guesthouse—one of the most distinctive luxury riverfront retreats near Louisville. Set along the scenic Ohio River in historic Jeffersonville, this beautifully restored 1800s estate blends timeless character, sweeping waterfront views, and elevated modern comfort for an unforgettable group getaway.
Start your mornings with coffee on the wraparound porch as the river comes alive, spend your afternoons exploring Downtown Louisville, the Bourbon Trail, Churchill Downs, NuLu, or the Big Four Bridge, then return home for evenings in the private hot tub, fireside conversations, outdoor dining, or stargazing inside the signature glass dome.
Thoughtfully designed for large groups, families, wedding parties, corporate retreats, Derby weekends, Bourbon Trail trips, and special celebrations, Deaconess Guesthouse offers the rare combination of space, privacy, style, and location.
✨ Why Guests Love Deaconess Guesthouse
• Luxury Riverfront Setting — Enjoy panoramic Ohio River views just minutes from Louisville’s top attractions.
• 8 Designer Bedrooms | Sleeps 24 — Spacious, comfortable accommodations for large groups without sacrificing privacy.
• 6 Spa-Inspired Bathrooms — Beautifully updated spaces designed for comfort and convenience.
• Four Fully Equipped Kitchens — Ideal for multi-family stays, private chefs, entertaining, and extended getaways.
• Historic Charm + Modern Luxury — Restored 1800s architecture paired with curated interiors, upscale finishes, and elegant gathering spaces.
• Resort-Style Outdoor Living — Private hot tub, fire pit, glass dome, gazebo dining, wraparound porches, balconies, and unforgettable riverfront sunsets.
• Walkable Jeffersonville Location — Stroll to cafés, restaurants, boutiques, parks, festivals, the waterfront, and the iconic Big Four Bridge.
• Minutes to Louisville — Easy access to Downtown Louisville, NuLu, Churchill Downs, Bourbon Trail distilleries, museums, concerts, nightlife, and major events.
• Family & Pet-Friendly Comfort — Thoughtfully curated for guests of all ages, including furry companions.
• Ample Free Parking — Private rear parking for up to 8 vehicles plus free street parking directly in front of the estate.
✨ The Experience
Deaconess Guesthouse is more than a place to stay—it is a luxury riverfront experience designed for connection, celebration, and unforgettable memories. From peaceful porch mornings and walkable waterfront adventures to hot tub evenings, fireside gatherings, and Derby or Bourbon Trail weekends, this historic estate offers a rare and elevated home base near Louisville.
Highly sought-after Derby, Bourbon Trail, wedding, and event weekends book quickly. Reserve your stay and experience one of the most unique luxury group retreats on the Ohio River.
** Please note: A strict cancellation policy applies for Derby and Bourbon & Beyond dates. **
★ CONVENIENT CENTRAL LOCATION
Perfectly located just minutes from Louisville’s top attractions, restaurants, nightlife, and event venues:
• Big Four Walking Bridge — 0.4 mi (2 mins)
• Downtown Louisville & 4th Street Live — 2.4 mi (6 mins)
• KFC Yum! Center — 2.3 mi (7 mins)
• Churchill Downs / Kentucky Derby — 7.7 mi (15 mins)
• Waterfront Park — 3.4 mi (9 mins)
• Louisville Airport (SDF) — 8.6 mi (10 mins)
• Kentucky Exposition Center & Fairgrounds — ~6.5 mi (10–11 mins)
• Kentucky Kingdom — 7.4 mi (13 mins)
• Highland Festival Grounds — 8.5 mi (12 mins)
• Louisville Mega Cavern — 10.2 mi (19 mins)
• UPS Worldport — 11.2 mi (20 mins)
• Valhalla Golf Club — 19 mi (27 mins)
• Waverly Hills Sanatorium — 17 mi (30 mins)
Most destinations are just a quick 10–15 minute Uber/Lyft ride away.
★ 2026 TOP EVENTS
• Run 4 Roses Basketball Tournament — Jul 9–14, 2026
• Kentucky State Fair — Aug 20–30, 2026
• Big Four Arts Festival — Sep 12–13, 2026
• Louder Than Life Festival — Sep 17–20, 2026
• Bourbon & Beyond Festival — Sep 24–27, 2026
• St. James Court Art Show — Oct 3–4, 2026
• NuLu Fest — Oct 9–11, 2026
• Halloween & Haunted Attractions — Oct 24–31, 2026
• Thanksgiving Week Travel — Nov 25–29, 2026
• Light Up Louisville — Nov 27, 2026
• Christmas at the Frazier Museum — Dec 2026
• Louisville Ballet’s The Nutcracker — Dec 2026
• New Year’s Eve at Fourth Street Live! — Dec 31, 2026
★ 2026 TRADE SHOWS & MAJOR EVENTS
• Equip Exposition — Oct 20–23, 2026
NOTE:
1. 25+ to book.
2. House Rules Required: E-sign rental agreement and submit a $500 security hold via secure OwnerRez (placed 2 days before arrival, released 7 days after departure if no damage).
3. Cancellation Policy: Please be aware that a strict cancellation policy is in effect for bookings during the Kentucky Derby and Bourbon & Beyond festival dates.
4. No visitors unless pre-approved by the host.
5. Exterior cameras only (parking area & front door). No interior or backyard cameras.
6. Dome use: Not recommended during hot summer months.
7. No early check-in / late check-out on same-day turnovers.
8. When available: $100 (≤2 hrs), $250 (2–4 hrs), full night rate (>4 hrs).
9. Refunds: Non-Airbnb refunds are subject to a 3% payment processing fee.
10. Optional Concierge Services: Enhance your stay with our optional services, including grocery pre-stocking, a private chef experience, or custom-chauffeured Bourbon Trail tours.
11. House-trained pets are welcomed. We do charge $300 for 1st pet and $250 for the 2nd pet. (max 2 pets, 50lbs max weight limit each).
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANKS!
Welcome to Deaconess Guesthouse—one of the most distinctive luxury riverfront retreats near Louisville. Set along the scenic Ohio River in historic Jeffersonville, this beautifully restored 1800s estate blends timeless character, sweeping waterfront views, and elevated modern comfort for an unforgettable group getaway.
Start your mornings with coffee on the wraparound porch as the river comes alive, spend your afternoons exploring Downtown Louisville, the Bourbon Trail, Churchill Downs, NuLu, or the Big Four Bridge, then return home for evenings in the private hot tub, fireside conversations, outdoor dining, or stargazing inside the signature glass dome.
Thoughtfully designed for large groups, families, wedding parties, corporate retreats, Derby weekends, Bourbon Trail trips, and special celebrations, Deaconess Guesthouse offers the rare combination of space, privacy, style, and location.
✨ Why Guests Love Deaconess Guesthouse
• Luxury Riverfront Setting — Enjoy panoramic Ohio River views just minutes from Louisville’s top attractions.
• 8 Designer Bedrooms | Sleeps 24 — Spacious, comfortable accommodations for large groups without sacrificing privacy.
• 6 Spa-Inspired Bathrooms — Beautifully updated spaces designed for comfort and convenience.
• Four Fully Equipped Kitchens — Ideal for multi-family stays, private chefs, entertaining, and extended getaways.
• Historic Charm + Modern Luxury — Restored 1800s architecture paired with curated interiors, upscale finishes, and elegant gathering spaces.
• Resort-Style Outdoor Living — Private hot tub, fire pit, glass dome, gazebo dining, wraparound porches, balconies, and unforgettable riverfront sunsets.
• Walkable Jeffersonville Location — Stroll to cafés, restaurants, boutiques, parks, festivals, the waterfront, and the iconic Big Four Bridge.
• Minutes to Louisville — Easy access to Downtown Louisville, NuLu, Churchill Downs, Bourbon Trail distilleries, museums, concerts, nightlife, and major events.
• Family & Pet-Friendly Comfort — Thoughtfully curated for guests of all ages, including furry companions.
• Ample Free Parking — Private rear parking for up to 8 vehicles plus free street parking directly in front of the estate.
✨ The Experience
Deaconess Guesthouse is more than a place to stay—it is a luxury riverfront experience designed for connection, celebration, and unforgettable memories. From peaceful porch mornings and walkable waterfront adventures to hot tub evenings, fireside gatherings, and Derby or Bourbon Trail weekends, this historic estate offers a rare and elevated home base near Louisville.
Highly sought-after Derby, Bourbon Trail, wedding, and event weekends book quickly. Reserve your stay and experience one of the most unique luxury group retreats on the Ohio River.
** Please note: A strict cancellation policy applies for Derby and Bourbon & Beyond dates. **
★ CONVENIENT CENTRAL LOCATION
Perfectly located just minutes from Louisville’s top attractions, restaurants, nightlife, and event venues:
• Big Four Walking Bridge — 0.4 mi (2 mins)
• Downtown Louisville & 4th Street Live — 2.4 mi (6 mins)
• KFC Yum! Center — 2.3 mi (7 mins)
• Churchill Downs / Kentucky Derby — 7.7 mi (15 mins)
• Waterfront Park — 3.4 mi (9 mins)
• Louisville Airport (SDF) — 8.6 mi (10 mins)
• Kentucky Exposition Center & Fairgrounds — ~6.5 mi (10–11 mins)
• Kentucky Kingdom — 7.4 mi (13 mins)
• Highland Festival Grounds — 8.5 mi (12 mins)
• Louisville Mega Cavern — 10.2 mi (19 mins)
• UPS Worldport — 11.2 mi (20 mins)
• Valhalla Golf Club — 19 mi (27 mins)
• Waverly Hills Sanatorium — 17 mi (30 mins)
Most destinations are just a quick 10–15 minute Uber/Lyft ride away.
★ 2026 TOP EVENTS
• Run 4 Roses Basketball Tournament — Jul 9–14, 2026
• Kentucky State Fair — Aug 20–30, 2026
• Big Four Arts Festival — Sep 12–13, 2026
• Louder Than Life Festival — Sep 17–20, 2026
• Bourbon & Beyond Festival — Sep 24–27, 2026
• St. James Court Art Show — Oct 3–4, 2026
• NuLu Fest — Oct 9–11, 2026
• Halloween & Haunted Attractions — Oct 24–31, 2026
• Thanksgiving Week Travel — Nov 25–29, 2026
• Light Up Louisville — Nov 27, 2026
• Christmas at the Frazier Museum — Dec 2026
• Louisville Ballet’s The Nutcracker — Dec 2026
• New Year’s Eve at Fourth Street Live! — Dec 31, 2026
★ 2026 TRADE SHOWS & MAJOR EVENTS
• Equip Exposition — Oct 20–23, 2026
NOTE:
1. 25+ to book.
2. House Rules Required: E-sign rental agreement and submit a $500 security hold via secure OwnerRez (placed 2 days before arrival, released 7 days after departure if no damage).
3. Cancellation Policy: Please be aware that a strict cancellation policy is in effect for bookings during the Kentucky Derby and Bourbon & Beyond festival dates.
4. No visitors unless pre-approved by the host.
5. Exterior cameras only (parking area & front door). No interior or backyard cameras.
6. Dome use: Not recommended during hot summer months.
7. No early check-in / late check-out on same-day turnovers.
8. When available: $100 (≤2 hrs), $250 (2–4 hrs), full night rate (>4 hrs).
9. Refunds: Non-Airbnb refunds are subject to a 3% payment processing fee.
10. Optional Concierge Services: Enhance your stay with our optional services, including grocery pre-stocking, a private chef experience, or custom-chauffeured Bourbon Trail tours.
11. House-trained pets are welcomed. We do charge $300 for 1st pet and $250 for the 2nd pet. (max 2 pets, 50lbs max weight limit each).
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANKS!
Amenities at 8BR Riverfront Escape w/Dome Firepit HotTub Views Luxe Amenities
Non-smoking
Pets allowed
Family friendly
Map of Jeffersonville, IN
Ratings and reviews
10 / 10Outstanding·Jan 2026
We Absolutely Loved Our Stay at Deaconess Guesthouse!We loved everything about this house! The tall ceilings, comfortable sitting areas, and the beautiful color palettes in each unit made it such a special and relaxing place to stay. The promotional boards with bits of history were so fun to read and gave the home extra character.The coffee bar was a huge hit with our group, and the little touches like the ice bucket and fully stocked bathrooms (shampoo, conditioner, and body wash) were so appreciated. It made our stay effortless knowing that everything we needed—paper towels, toilet paper, sponges, towels—was already provided.The place was spotless when we arrived, and it was such a treat to have TVs in every room. We really enjoyed the hot tub, and when we had a small issue, someone came right away—not only to fix it but also to clean it thoroughly. The responsiveness was top-notch. Even when we asked for a vacuum, it was delivered immediately!This property is beautifully maintained and exceptionally well-managed. We would absolutely stay here again and highly recommend it to anyone visiting Jeffersonville or the Louisville area!
10 / 10Outstanding·Dec 2025
The house is big and unique. There are four areas that could be separate spaces - each includes a living area, kitchen, bathroom, and two bedrooms. We were able to gather together when we wanted to and have our own space to sleep. The teens enjoyed the hot tub, and the younger kids liked the games. The location is great. We walked along the river and to the hub of town. Highly recommend.
10 / 10Outstanding·Dec 2025
Another great stay at The Deaconess House! This was a repeat stay for our annual sales and marketing strategic planning and everything about our stay was great! Communication prior to and during the stay was excellent. The property was as described, all 4 units were fully stocked and more than met our needs. We had 8 adults staying plus had visitors one evening for a special dinner and the home provided plenty of room for everyone. We will likely return for a third visit next year and we highly recommend this property!
10 / 10Outstanding·Nov 2025
We had a wonderful experience! Probably the best rental I've ever stayed in. It was very clean, wonderful amenities and the host was very attentive. Checking on us several times. We will highly recommend and hope to stay again!!
$$$$
Top rated by guests
10Outstanding
(25 Ratings)
"We Absolutely Loved Our Stay at Deaconess Guesthouse!We loved everything about this house! The tall ceilings, comfortable sitting areas, and the beautiful color palettes in each unit made it such a sp..."
Michelle C.Don't miss out! Price and availability may change
